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Thursday September 12th |
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15.00 - 17.00 |
Arrival and Registration |
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17.00 - 17.15 |
Welcome |
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Peter R Mertens |
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17.15 - 17.45 |
Welcome lecture: |
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"Scientific landscape in Magdeburg" |
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Burkhart Schraven |
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18.30 - 21.00 |
Dinner on the shore of the Elbe |
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Friday September 13th |
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Scientific Session 1 "Biochemistry, Structure & Function" |
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Chairs: Annette Lasham (Auckland, New Zealand)/ Jonathan Lindquist (Magdeburg, Germany) |
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08.30 - 08.55 |
Mini Lecture: "Crystal Structures of cold shock proteins" |
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Udo Heinemann (Berlin, Germany) |
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08.55 - 09.10 |
Short communication: „Stress-induced phosphorylation and nuclear translocation of YB-1“ Mahmoud Toulany (Tübingen, Germany) |
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09.10 - 09.25 |
Short communication: “Full length Y-box-binding protein localises to the nucleus during the G2 phase of the cell cycle” Adele Woolley (Dunedin, New Zealand) |
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09.25 - 09.40 |
Short communication: „Activation of NFĸB requires Y-box binding protein 1“ Aneri Shah (Magdeburg, Germany)
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09.40 - 09.55 |
Short communication: “The mechanisms of YB-1 translocation to the nucleus” |
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Daria Mordovkina (Pushchino, Russia) |
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09.55 - 10.35 |
Tea & Coffee |
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Scientific Session 2 "Cell homeostasis" |
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Chairs: Mahmoud Toulany (Tübingen, Germany)/ Monika Brunner-Weinzierl (Magdeburg, Germany) |
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10.35 - 11.00 |
Mini Lecture: “YB-1: Master regulator of cytokinesis” Antony Braithwaite (Dunedin, New Zealand) |
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11.00 - 11.25
11.25 - 11.50 |
Mini Lecture: “YB-1 as a master regulator of epidermal stem cell fate decisions” Anna Mandinova (Boston, USA)
Mini Lecture: "High salt dependent kidney damage accompanied glucosuria/proteinuria is prevented by Ybx1 deletion" |
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Anja Bernhardt (Magdeburg, Germany) |
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11.50 - 12.15 |
Mini Lecture: “Effects of recombinant YB-1 on trophoblast cell function” Ana Zenclussen/ Anne Schumacher (Magdeburg, Germany) |
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12.15 - 12.40 |
Mini Lecture: “The cold shock Y-box protein-1 (YB-1) controls T-cell homeostasis and its relevance for immune pathologies” Monika Brunner-Weinzierl (Magdeburg, Germany) |
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12.40 - 13.40 |
Lunch |
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Scientific Session 3 "Cell transformation & Cancer" |
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Chairs: Anna Mandinova (Boston, USA)/ Johannes Haybäck (Magdeburg, Germany) |
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13.40 - 14.05 |
Mini Lecture: "Targeting the evolution of persistent clones in Jak2-mutated neoplasms” |
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Florian Heidel (Jena, Germany) |
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14.05 - 14.20 |
Short communication: “YBX1 determines cell-competitivity in Acute Myeloid Leukemia by translational control of oncogenic drivers.” Florian Perner (Boston, USA) |
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14.20 - 14.45 |
Mini Lecture: "Participation of cold shock proteins in hepatic progenitor cell-mediated liver regeneration and hepatic carcinogenesis." |
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Honglei Weng (Mannheim, Germany) |
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14.45 - 15.00 |
Short communication: “Inhibiting YB-1 activation by targeting RSK: a novel strategy for cancer therapy” Sunali Metha (Dunedin, New Zealand)
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15.00 - 15.15 |
Short communication: „YB-1 and translation initiation in the context of cancer“ Johannes Haybäck (Magdeburg, Germany)
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15.15 - 15.45 |
Tea & Coffee |
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Scientific Session 4 "Cell transformation & Cancer" |
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Chairs: Antony Braithwaite (Auckland, New Zeeland) / Ute Raffetseder (Aachen, Germany) |
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15.45 - 16.10 |
Mini Lecture: "title has to be announced” |
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Cheng Zhu () |
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16.10 - 16.25 |
Short communication: “YB-1 phosphorylation as an effective therapeutic target in human progressive cancers” Tomohiro Shibata (Fukuoka, Japan)
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16.25 - 16.50 |
Mini Lecture: “YB-1: Master-regulator of aggressive behavior in malignant pleural mesothelioma” |
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Karin Schelch (Vienna, Austria) |
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17.30 - 21.30 |
Dinner cruise on the river Elbe |
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Saturday September 14th |
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Scientific Session 5 "Inflammation and disease" |
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Chairs: Mayumi Ono (Fukuoka, Japan)/ Florian Heidel (Jena, Germany) |
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09.00 - 09.25 |
Mini Lecture: "Regulation of the cold shock protein YB-1 by coagulation proteases in renal disease” |
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Berend Isermann (Leipzig, Germany) |
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09.25 - 09.40 |
Short communication: “YB-1 mediated CXCL-1 expression decides on kidney damage in liver fibrosis” Daniela Hermert (Aachen, Germany)
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09.40 - 09.55 |
Short communication: “Regulation of cold shock protein YB-1 expression and modification in immune cells” Xenia Gorny (Magdeburg, Germany)
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09.55 - 10.10 |
Short communication: Mapping local protein interactomes of eIF3A using proximity-dependent biotin identification (BioID) and the involvement of YB-1 Diep-Khanh Vo (Magdeburg, Germany) |
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10.10 - 10.25 |
Short communication: “Understanding the role of YB-1 in glioblastoma multiforme” Jingyi Hui (Shanghai, China)
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10.25 - 10.50 |
Mini Lecture: "Participation of cold shock DNA-binding protein A in inflammatory diseases." |
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Peter Mertens (Magdeburg, Germany) |
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10.50 - 11.15 |
Tea & Coffee |
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Scientific Session 6 "Extracellular functions" |
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Chairs: Cheng Zhu (Hangzhou, China)/ Berend Isermann (Leipzig, Germany) |
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11.15 - 11.40 |
Mini Lecture: "Fibrosis and immune cell infiltration are separate events regulated by cell-specific Notch3 expression" Sabine Brandt (Magdeburg, Germany) |
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11.40 - 11.55 |
Short communication: “The YB-1:Notch-3 axis modulates immune cell responses and organ damage in systemic lupus erythematosus” Daniel Breitkopf (Aachen, Germany)
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11.50 - 12.05 |
Short communication: “Role of evolutionary conserved cold shock protein YB-1 in unidirectional glomerular tubular communication in diabetic kidney disease.” Rajiv Rana (Leipzig, Germany) |
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12.05 - 12.20 |
Short communication: “YB-1 deficiency protects from Experimental Cerebral Malaria” |
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Nishanth Gopala (Hannover, Germany) |
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12.20 - 12.35 |
Short communication: “In and outside the melanoma cell: The Y-box binding protein 1 as a novel tumour marker and functional player in melanoma progression” Corinna Kosnopfel (Tübingen , Germany) |
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12.35 - 12.50 |
Short communication: “YB-1: a bridge between the circadian clock and cell cycle control” Viola Calabro (Naples, Italy) |
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12.50 - 14.00 |
Lunch |
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14.00 - 17.30 |
bicycle tour along the river Elbe |
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Scientific Session 7 "Animal models/ Therapeutic and diagnostic tools" |
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Chairs: Honglei Weng (Mannheim, Germany)/ Ashutosh Mani (Allahabad, India) |
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17.30 - 17.45 |
Short communication: “Cold shock proteins interfere with TNFα binding to its receptor and modulate progranulin-mediated inhibition of signaling” |
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Jonathan Lindquist (Magdeburg, Germany) |
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17.45 - 18.10 |
Mini Lecture: "Therapeutic nuclear shuttling of YB-1 reduces renal damage and fibrosis." |
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Ute Raffetseder (Aachen, Germany) |
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18.10 - 18.35 |
Mini Lecture: "YB-1: oncoprotein, prognostic marker and therapeutic target." |
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Annette Lasham (Auckland, New Zeeland) |
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18.35 - 19.00 |
Business Meeting about the prospect to perform regular joint meetings |
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20.00 – open end |
Dinner Lukasklause with live band |
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